Oligomerization of Human Gadd45a Protein

Protein Oligomerization

Hantavirus nucleocapsid protein oligomerization.

Hantaviruses are enveloped, negative-strand RNA viruses which can be lethal to humans, causing either a hemorrhagic fever with renal syndrome or a hantaviral pulmonary syndrome. The viral genomes consist of three RNA segments: the L segment encodes the viral polymerase, the M segment encodes the viral surface glycoproteins G1 and G2, and the S segment encodes the nucleocapsid (N) protein. The N...

Control of Protein Oligomerization and De-oligomerization on Lipid Membranes

Aalto University, P.O. Box 11000, FI-00076 Aalto www.aalto.fi Author Ajay Mahalka Name of the doctoral dissertation Control of Protein Oligomerization and De-oligomerization on Lipid Membranes Publisher School of Science Unit Department of Biomedical Engineering and Computational Science Series Aalto University publication series DOCTORAL DISSERTATIONS 220/2013 Field of research Biomedical Engi...

Monitoring peripheral protein oligomerization on biological membranes.

Peripheral proteins transiently interact with cellular membranes where they regulate important cellular events such as signal transduction. A number of peripheral proteins harbor lipid-binding modules that not only bind selectively with nanomolar affinity to biological membranes but also oligomerize on the membrane surface. In some cases, specific lipid binding or specific lipid compositions ca...

Membrane orientation and oligomerization of the small hydrophobic protein of human respiratory syncytial virus.

Previous work has demonstrated that the small hydrophobic (SH) protein of human respiratory syncytial virus (RSV) A2 strain is a 64 amino acid integral membrane protein that accumulates intracellularly as an unglycosylated major species (SH0), a minor species truncated at the amino terminus and two N-glycosylated species one of which contains a further addition of polylactosamine. In this study...